Flechner Stuart M, Saad Ismail R, Tiong Ho Y, Rabets John, Krishnamurthi Venkatesh
Glickman Urological and Kidney Institute, Cleveland Clinic Lerner College of Medicine, Cleveland, OH 44195, USA.
Pediatr Transplant. 2011 Feb;15(1):53-7. doi: 10.1111/j.1399-3046.2010.01410.x. Epub 2010 Oct 8.
We performed three cases of donor bladder trigone facilitated transplantation using pediatric en bloc kidneys into adult recipients. The donors were aged 11, 21, and 23 months; two of the donors were male, and the other was a female. In each case, the donor bladder was removed and the trigone was fashioned into a patch that contained both ureters, which was attached to the recipient anterior bladder wall. The recipients of the two male donor transplants healed and have normal voiding with no evidence of vesico-ureteral reflux. At 14 and 12 months, they have a creatinine of 1.2 and 1.0 mg/dL. The recipient of the female donor transplant developed a pelvic abscess, which necessitated reconstruction of the donor ureters and patch. She is now nine months with a creatinine of 1.2 mg/dL and voiding well. The use of the donor bladder trigone to facilitate pediatric en bloc transplantation can be carried out safely using the male donor urinary tract. However, the use of a female donor for this procedure may be a special circumstance requiring increased attention to sterilize the small donor introitus and avoiding devascularization of the bladder trigone that is adherent to the anterior vaginal wall.
我们进行了3例利用小儿整块肾脏向成年受者进行供体膀胱三角区辅助移植的手术。供体年龄分别为11、21和23个月;其中两名供体为男性,另一名为女性。每例手术中,均切除供体膀胱,并将三角区制成包含双侧输尿管的补片,然后将其附着于受者膀胱前壁。两名男性供体移植受者均愈合良好,排尿正常,无膀胱输尿管反流迹象。在术后14个月和12个月时,他们的肌酐水平分别为1.2和1.0mg/dL。女性供体移植受者发生了盆腔脓肿,需要对供体输尿管和补片进行重建。她现在术后9个月,肌酐水平为1.2mg/dL,排尿良好。利用男性供体尿路,安全地进行供体膀胱三角区辅助小儿整块移植是可行的。然而,将女性供体用于该手术可能是一种特殊情况,需要更加注意对供体小阴唇进行消毒,并避免附着于阴道前壁的膀胱三角区发生缺血。