Ciancio Gaetano, Kato Tomoaki, Chen Linda, Sageshima Junichiro, Livingstone Alan S, Burke George W
The Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA.
Transpl Int. 2009 Mar;22(3):350-3. doi: 10.1111/j.1432-2277.2008.00815.x.
The success of transplantation of the urinary bladder en bloc with pediatric kidneys remains undetermined. We transplanted a large portion of the bladder with en bloc kidney allografts from a 13-month-old donor into a 45-year-old adult male. The recipient, who was on long-term hemodialysis, had a small urinary bladder consistent with long-standing anuria. Informed consent was given and bilateral kidneys were transplanted en bloc with both ureters and bladder. The patient's bladder was augmented with the donor bladder and bilateral ureteroneocystotomies of small ureters was avoided. At 3 and 18 months post-transplantation, cystoscopies revealed a viable bladder with new vessels and normal donor bladder. Cystogram revealed no reflux. The bladder segment was reperfused via blood supply from both ureters and then from the recipient's bladder. It seems that bladder transplantation en bloc with pediatric kidneys is a viable option for augmentation of a small recipient bladder that allows avoidance of very small bilateral ureteroneocystotomies.
小儿肾脏整块移植膀胱的成功率仍未确定。我们将一名13个月大供体的大部分膀胱与整块肾移植给了一名45岁的成年男性。该接受者长期接受血液透析,其膀胱较小,符合长期无尿的情况。我们获得了知情同意,并将双侧肾脏与双侧输尿管和膀胱整块移植。用供体膀胱扩大了患者的膀胱,并避免了小输尿管的双侧输尿管膀胱吻合术。移植后3个月和18个月,膀胱镜检查显示膀胱存活,有新血管,供体膀胱正常。膀胱造影显示无反流。膀胱段通过双侧输尿管供血,然后通过接受者的膀胱供血重新灌注。看来,小儿肾脏整块移植膀胱是扩大小接受者膀胱的一种可行选择,可避免进行非常小的双侧输尿管膀胱吻合术。