Department of Dermatology, Venereology and Allergy, University of Essen, Germany.
J Dtsch Dermatol Ges. 2011 Feb;9(2):116-21. doi: 10.1111/j.1610-0387.2010.07535.x. Epub 2010 Oct 14.
The etiology of chronic leg ulcers is heterogenous and they exhibit quite different healing rates depending on the underlying cause. Although the prevalence and incidence of chronic leg ulcers appear to be increasing, data on these patients in Germany are lacking.
Altogether 100 German wound care professionals were asked to complete a questionnaire regarding the diagnosis and etiology of their patients with chronic leg ulcers.
We received the data on 31,619 patients. In these patients, venous insufficiency was the dominating causative factor in 47.6 % and arterial insufficiency in 14.5 %, 17.6 % of ulcers were due to combined arterial and venous insufficiency. Rarer causes included vasculitis (5.1 %), exogenous factors (3.8 %), pyoderma gangrenosum (3.0 %), infection (1.4 %), neoplasia (1.1 %), calciphylaxis (1.1 %) and drug-induced (1.1 %). The used diagnostic methods used varied widely between the medical and surgical specialties.
Even though the results of our study cannot claim to be a representative overview, they demonstrate clearly that next to known etiologies, e. g. chronic venous insufficiency or peripheral arterial insufficiency, which are relevant in 79.7 % of all patients a multitude of other causes exist, which are responsible in 20.3 % of all patients for the development of chronic leg ulcers.
慢性腿部溃疡的病因多种多样，根据其潜在病因，其愈合速度也有明显差异。尽管慢性腿部溃疡的患病率和发病率似乎在上升，但德国缺乏这些患者的数据。
共邀请了 100 名德国伤口护理专业人员填写一份关于他们慢性腿部溃疡患者的诊断和病因的问卷。
我们收到了 31619 名患者的数据。在这些患者中，静脉功能不全是主要致病因素，占 47.6%，动脉功能不全占 14.5%，17.6%的溃疡是由动静脉联合功能不全引起的。较罕见的病因包括血管炎（5.1%）、外源性因素（3.8%）、坏疽性脓皮病（3.0%）、感染（1.4%）、肿瘤（1.1%）、钙化性尿毒症性小动脉病（1.1%）和药物诱导的（1.1%）。不同的医疗和外科专科使用的诊断方法差异很大。
尽管我们的研究结果不能声称是代表性的概述，但它们清楚地表明，除了已知的病因，如慢性静脉功能不全或外周动脉功能不全，在所有患者中占 79.7%，还有许多其他病因，在所有患者中占 20.3%，导致慢性腿部溃疡的发生。
