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乳腺叶状囊肉瘤:一例 12 岁女童病例报告。

Cystosarcoma phyllodes of the breast: a case report in a 12-year-old girl.

机构信息

Department of Pediatrics, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

出版信息

Clin Transl Oncol. 2010 Oct;12(10):704-6. doi: 10.1007/s12094-010-0581-x.

Abstract

Breast tumors in adolescents are very rare and mostly benign. Fibroadenomas are the most frequent, but within the extensive differential diagnosis, the phyllodes tumor must be mentioned, which accounts for about 1% of breast tumors and the diagnosis of which is very rare in patients younger than 20 years. There are no specific symptoms or radiological images to distinguish phyllodes tumor from fibroadenoma; therefore, histological examination is mandatory for diagnosis. Histology also allows the classification of phyllodes tumor into benign, borderline, or malignant types for appropriate surgical treatment: freemargin excision in benign tumors and mastectomy in the other two types. Fortunately, the majority of these tumors are benign, and treatment maximizes breast conservation with free infiltration margins surgery, given that this fact is the most important factor to prevent local recurrence. In this article, we describe a rare case of borderline cystosarcoma phyllodes in a 12-year-old girl.

摘要

青少年的乳腺肿瘤非常罕见,且大多为良性。纤维腺瘤最为常见,但在广泛的鉴别诊断中,必须提到叶状肿瘤,其占乳腺肿瘤的 1%左右,而在 20 岁以下的患者中,这种肿瘤的诊断非常罕见。没有特定的症状或影像学图像可以将叶状肿瘤与纤维腺瘤区分开来;因此,必须进行组织学检查以明确诊断。组织学检查还可以将叶状肿瘤分为良性、交界性或恶性类型,以便进行适当的手术治疗:良性肿瘤行边缘自由切除,后两种类型行乳房切除术。幸运的是,这些肿瘤大多数为良性,治疗以最大限度地保留乳房为目标,采用游离浸润边缘手术,因为这一事实是预防局部复发的最重要因素。本文描述了一例罕见的 12 岁女孩交界性囊肉瘤叶状肿瘤。

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