Department of Radiology, Hacettepe University, Ankara, Turkey.
AJNR Am J Neuroradiol. 2011 Jan;32(1):179-84. doi: 10.3174/ajnr.A2237. Epub 2010 Oct 14.
SBO is a life-threatening infection that may have radiologic features similar to those of the neoplastic processes. The purpose of this study was to evaluate the DWI findings in SBO to facilitate the differential diagnosis.
The MR imaging findings of 9 patients with SBO were retrospectively evaluated and compared with MR imaging studies from 9 patients with NPC, 9 with lymphoma, and 9 with metastatic disease of the skull base. ADC measurements were performed from the ADC(ST) and the ADC(NST) in all 4 groups.
The mean ADC(ST) values were 1.26 ± 0.19 × 10(-3) mm(2)/s for SBO, 0.74 ± 0.18 × 10(-3) mm(2)/s for NPC, 0.59 ± 0.11 × 10(-3) mm(2)/s for lymphoma, and 0.99 ± 0.34 × 10(-3) mm(2)/s for metastatic disease, respectively. The mean ADC value of SBO was significantly higher than those of NPC and lymphoma (P < .0001). There was no significant difference for the comparison of SBO and metastatic lesions. When an ADC value equal to or higher than 1.08 × 10(-3) mm(2)/s was used to rule out lymphoma and NPC, the accuracy was 96%.
Although SBO is a relatively rare condition, its differential diagnosis from neoplastic processes of the skull base is essential to start appropriate treatment promptly. ADC values may help to distinguish patients with SBO from those with malignant lesions.
SBO 是一种危及生命的感染，其放射学特征可能与肿瘤过程相似。本研究旨在评估 SBO 的 DWI 表现，以促进鉴别诊断。
回顾性分析 9 例 SBO 患者的 MR 成像表现，并与 9 例 NPC、9 例淋巴瘤和 9 例颅底转移瘤患者的 MR 成像研究进行比较。对所有 4 组患者进行 ADC（ST）和 ADC（NST）的 ADC 测量。
SBO 的平均 ADC（ST）值为 1.26±0.19×10(-3)mm(2)/s，NPC 为 0.74±0.18×10(-3)mm(2)/s，淋巴瘤为 0.59±0.11×10(-3)mm(2)/s，转移瘤为 0.99±0.34×10(-3)mm(2)/s。SBO 的平均 ADC 值明显高于 NPC 和淋巴瘤（P<0.0001）。SBO 与转移性病变之间的比较无显著差异。当使用等于或高于 1.08×10(-3)mm(2)/s 的 ADC 值排除淋巴瘤和 NPC 时，准确率为 96%。
尽管 SBO 是一种相对罕见的疾病，但及时开始适当治疗需要对其与颅底恶性肿瘤进行鉴别诊断。ADC 值可能有助于区分 SBO 患者与恶性病变患者。
