内侧缰核对牙髓刺激诱发的张口反射的抑制作用。
Inhibitory effect of entopeduncular nucleus on the jaw-opening reflex induced by the tooth pulp stimulation.
作者信息
Kawarada K, Kowada K, Matsumoto N, Suzuki T A
机构信息
Department of Oral Physiology, School of Dentistry, Iwate Medical University, Morioka, Japan.
出版信息
Jpn J Physiol. 1990;40(6):921-8. doi: 10.2170/jjphysiol.40.921.
The effect of stimulation of the entopeduncular nucleus (EP) on the jaw-opening reflex (JOR) was studied in the cat anesthetized with sodium pentobarbital. JOR was quantified by the digastric electromyogram. The conditioning stimulation (train of 33 pulses at 330 Hz, 0.5 ms duration, 50-400 microA) of the EP powerfully inhibited the JOR induced by the tooth pulp stimulation. Conditioning stimulation with 300 microA produced inhibition which continued approximately 400 ms from the cessation of the stimulation. The injection of monosodium glutamate into EP elicited inhibition of the JOR that lasted about 15 min. Additionally, the conditioning stimulation inhibited the JOR induced by the stimulation of trigeminal rostral and caudal nuclei in a similar manner but not jaw-opening response induced by the stimulation of the trigeminal motor nucleus. Therefore, it is possible that the excitation of the EP exerts inhibitory modulation of JOR at the motor nucleus rather than the trigeminal sensory nucleus.
在戊巴比妥钠麻醉的猫中，研究了刺激内侧缰核（EP）对张口反射（JOR）的影响。通过二腹肌肌电图对JOR进行量化。EP的条件刺激（330 Hz、持续时间0.5 ms、50 - 400 μA的33个脉冲串）强烈抑制牙髓刺激诱导的JOR。300 μA的条件刺激产生的抑制作用在刺激停止后持续约400 ms。向EP注射谷氨酸钠引起JOR抑制，持续约15分钟。此外，条件刺激以类似方式抑制三叉神经吻侧和尾侧核刺激诱导的JOR，但不抑制三叉神经运动核刺激诱导的张口反应。因此，EP的兴奋可能在运动核而非三叉神经感觉核发挥对JOR的抑制性调制作用。
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