刺激猫的中央杏仁核抑制下颌张开反射。

Inhibition of jaw-opening reflex by stimulation of the central amygdaloid nucleus in the cat.

作者信息

Kowada K, Kawarada K, Matsumoto N, Ooe M, Suzuki T A

机构信息

Department of Oral Physiology, School of Dentistry, Iwate Medical University, Morioka, Japan.

出版信息

Jpn J Physiol. 1991;41(3):513-20. doi: 10.2170/jjphysiol.41.513.

DOI:10.2170/jjphysiol.41.513

PMID:1960893

Abstract

The effect of stimulation of the amygdaloid complex on the jaw-opening reflex (JOR) was studied in the cat anesthetized with pentobarbital sodium. The conditioning stimulation of the central amygdaloid nucleus (ACE), but not the other amygdaloid nuclei, markedly inhibited the JOR induced by the tooth pulp stimulation. Ipsilateral ACE conditioning stimulation with 300 microA produced inhibition which lasted approximately 500 ms from the cessation of the stimulation. Additionally, the microinjection of monosodium glutamate into ACE elicited inhibition of the JOR that lasted about 10 min. These findings suggest that the excitation of the cell bodies in ACE exerts inhibitory action on the trigeminal nociceptive reflex.

摘要

在戊巴比妥钠麻醉的猫中，研究了杏仁复合体刺激对下颌张开反射（JOR）的影响。中央杏仁核（ACE）的条件刺激，而非其他杏仁核，显著抑制了牙髓刺激诱发的JOR。用300微安进行同侧ACE条件刺激产生的抑制作用，从刺激停止后持续约500毫秒。此外，向ACE微量注射谷氨酸可引发JOR抑制，持续约10分钟。这些发现表明，ACE中细胞体的兴奋对三叉神经伤害性反射发挥抑制作用。