Department of Haematology, West Glasgow Teaching Hospital, Gartnavel General Hospital, Glasgow, UK.
J Clin Pathol. 2010 Dec;63(12):1124-6. doi: 10.1136/jcp.2010.083188. Epub 2010 Oct 14.
To examine serum ferritin values in iron-replete patients in primary care and determine the action taken on those patients with very high values (>1000 μg/l).
Serum ferritin values from 4170 consecutive patients in primary care were examined. All measurements had been made at the request of the general practitioner.
Ferritin values in males reached a steady state by 30 years and did not increase thereafter. Values above 300 μg/l were found in 17% of all males. Female values rose progressively with age. Less than 10% of women <50 years had values >100 μg/l. By the age of 70 years, 8% had values >300 μg/l. Ferritin values >1000 μg/l were found in 59 patients. This rise was neither explained nor investigated in 32 cases.
Raised ferritin values are frequently found in samples submitted from primary care and most so in adult males. The authors also conclude that general practitioners require more guidance from haematologists in the management of patients with very high values.
检测初级保健中铁充足患者的血清铁蛋白值，并确定对那些血清铁蛋白值非常高（>1000μg/l）的患者采取的措施。
检测了初级保健中 4170 名连续患者的血清铁蛋白值。所有测量均由全科医生要求进行。
男性的铁蛋白值在 30 岁时达到稳定状态，此后不再增加。所有男性中，有 17%的铁蛋白值>300μg/l。女性的铁蛋白值随年龄逐渐升高。<50 岁的女性中，不到 10%的人铁蛋白值>100μg/l。到 70 岁时，8%的人铁蛋白值>300μg/l。有 59 名患者的铁蛋白值>1000μg/l。32 例患者的铁蛋白值升高既未得到解释也未进行调查。
初级保健中提交的样本中经常发现铁蛋白值升高，成年男性中最常见。作者还认为，全科医生在处理铁蛋白值非常高的患者时，需要更多血液学家的指导。
