Ushijima Michiyo, Yamakawa Yoshihiro, Sakabe Eriko, Waki Hiroki, Katou Kiyoshi
Department of Obstetrics and Gynecology, Takaoka City Hospital.
Gan To Kagaku Ryoho. 2010 Oct;37(10):2003-5.
A 52-year-old woman with recurrent high-grade endometrial stromal sarcoma presented with left hypochondralgia. She had undergone total hysterectomy and bilateral salpingo-oophorectomy for the disease over the past six months, and preferred not to receive additional treatment. The following regimen of chemotherapy was given: each course consisted of ifosfamide (1,000 mg/m²) on days 1-5, adriamycin (60 mg/m²) on day 1, and cisplatin (15 mg/m²) on days 1-5. After 4 courses of the chemotherapy, the intraabdominal mass and multiple pulmonary nodules were reduced 45. 1% from the beginning. This case suggests that IAP might be effective chemotherapy for patients with high-grade endometrial stromal sarcoma.
一名52岁复发性高级别子宫内膜间质肉瘤女性患者出现左季肋部疼痛。在过去6个月里，她因该病接受了全子宫切除术和双侧输卵管卵巢切除术，且不愿接受进一步治疗。给予以下化疗方案：每个疗程包括第1 - 5天的异环磷酰胺（1000 mg/m²）、第1天的阿霉素（60 mg/m²）以及第1 - 5天的顺铂（15 mg/m²）。化疗4个疗程后，腹腔肿块和多个肺结节较初始时缩小了45.1%。该病例提示IAP可能是高级别子宫内膜间质肉瘤患者有效的化疗方法。
