Liu Yilun, Conaway Joan W
Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520-8040, USA.
F1000 Biol Rep. 2009 Oct 14;1:76. doi: 10.3410/B1-76.
Since the cloning of the first human RECQ gene, RECQ1, more than 15 years ago, RECQ helicases have been a major focus in cancer research. Recent studies of human RECQ protein complexes are providing insight into their roles in various DNA metabolic pathways that protect the integrity of our genome.
自15多年前首次克隆出人类RECQ基因RECQ1以来，RECQ解旋酶一直是癌症研究的主要焦点。最近对人类RECQ蛋白复合物的研究正在深入了解它们在保护我们基因组完整性的各种DNA代谢途径中的作用。
