RecA结构的意义。
Implications of the RecA structure.
作者信息
Egelman Edward H
机构信息
Department of Biochemistry and Molecular Genetics, University of Virginia Box 800733, Charlottesville, VA 22908-0733 USA.
出版信息
F1000 Biol Rep. 2009 Jan 21;1:7. doi: 10.3410/B1-7.
Abstract
The RecA protein has been the most intensively studied protein involved in homologous genetic recombination, but until recently very little has been known about the molecular details of how RecA can bring two DNA molecules into juxtaposition and switch strands between them. A recent RecA-DNA crystal structure provides some striking new insights.
摘要
RecA蛋白是参与同源基因重组的研究最为深入的蛋白，但直到最近，对于RecA如何使两个DNA分子并列并在它们之间进行链交换的分子细节仍知之甚少。最近的RecA-DNA晶体结构提供了一些惊人的新见解。
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