Kochar Rajan, Dupont Andrew W
Division of Gastroenterology, Hepatology & Nutrition, The University of Texas Health Science Center at Houston 6431 Fannin Street, MSB 4.234, Houston, TX 77030 USA.
F1000 Med Rep. 2010 Apr 12;2:26. doi: 10.3410/M2-26.
Gastric variceal bleeding is a common problem in patients with cirrhosis and is associated with increased morbidity and mortality. Management is complex and includes pharmacotherapy, endoscopic therapy, and shunt placement. Recent studies indicate that endoscopic therapy with tissue adhesives has similar hemostasis rates and outcomes in terms of mortality as shunt placement but has a lower complication rate and therefore could be considered the first line therapy for acute bleeding and secondary prophylaxis of gastric varices.
胃静脉曲张出血是肝硬化患者的常见问题，与发病率和死亡率增加相关。治疗较为复杂，包括药物治疗、内镜治疗和分流术。近期研究表明，使用组织粘合剂的内镜治疗在止血率和死亡率方面与分流术相似，但并发症发生率较低，因此可被视为胃静脉曲张急性出血和二级预防的一线治疗方法。
