Department of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow, UK.
Mar Drugs. 2010 Aug 5;8(8):2267-300. doi: 10.3390/md8082267.
Scandinavian folk medicine used shark liver oil for the treatment of cancers and other ailments based on the rarity of tumors in sharks and their ability to resist infections. Shark liver oil is a source of alkylglycerols which have been studied as anti-cancer agents in several clinical trials. Moreover, alkylglycerols have been investigated for the treatment of radiation induced side effects and for their ability to boost the immune system. Several experimental studies have shown the ability of alkylglycerols to open the blood brain barrier to facilitate the access of therapeutic drugs to the central nervous system. This review covers the most important studies of alkylglycerols in both animals and humans.
斯堪的纳维亚民间医学曾使用鲨鱼肝油来治疗癌症和其他疾病，其依据是鲨鱼很少长肿瘤以及它们抗感染的能力。鲨鱼肝油是烷氧基甘油的一个来源，在几项临床试验中，烷氧基甘油已被研究为抗癌药物。此外，烷氧基甘油还被用于治疗辐射引起的副作用，并因其增强免疫系统的能力而受到研究。几项实验研究表明，烷氧基甘油能够打开血脑屏障，使治疗药物更容易进入中枢神经系统。这篇综述涵盖了烷氧基甘油在动物和人类中最重要的研究。
