Visscher Susan H, Van Minnen Baucke, Bos Rudolf R M
Department of Oral and Maxillofacial Surgery, University of Groningen, Groningen, The Netherlands.
J Oral Maxillofac Surg. 2011 Feb;69(2):390-5. doi: 10.1016/j.joms.2010.05.014. Epub 2010 Oct 14.
To assess the feasibility of a conically shaped biodegradable polyurethane (PU) foam for closure of oroantral communications (OACs).
In 10 consecutive patients, fresh OACs (present for <24 hours) were closed with PU foam. Standardized evaluations were performed at 2 and 8 weeks after closure of the OAC. Success was considered permanent closure of the OAC.
No complications were observed in 7 of the 10 patients. Of the other 3 patients, 1 developed a maxillary sinusitis that was successfully managed with antibiotics and the OAC recurred in 2 patients.
Permanent closure of the OAC using PU foam was accomplished in 8 of 10 patients. The results obtained in the present study were more favorable than in a previous feasibility study. Therefore, the alterations in the treatment protocol were maintained for additional research of this new and straightforward treatment strategy. In general, closure of OACs with biodegradable PU foam is feasible and has the potential to make surgical treatment unnecessary for a large number of patients with OACs.
评估锥形可生物降解聚氨酯（PU）泡沫用于封闭口腔上颌窦瘘（OAC）的可行性。
连续10例患者，采用PU泡沫封闭新鲜的OAC（存在时间<24小时）。在OAC封闭后2周和8周进行标准化评估。成功定义为OAC永久性封闭。
10例患者中有7例未观察到并发症。另外3例患者中，1例发生上颌窦炎，经抗生素治疗成功，2例患者OAC复发。
10例患者中有8例使用PU泡沫实现了OAC的永久性封闭。本研究获得的结果比先前的可行性研究更理想。因此，维持治疗方案的改变以对这种新的简单治疗策略进行进一步研究。总体而言，用可生物降解PU泡沫封闭OAC是可行的，并且有可能使大量OAC患者无需手术治疗。
