Visscher Susan H, van Minnen Baucke, Bos Rudolf R M
Department of Oral and Maxillofacial Surgery, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
J Oral Maxillofac Surg. 2010 Feb;68(2):281-6. doi: 10.1016/j.joms.2009.07.019. Epub 2010 Jan 15.
The aim of this study was to assess the feasibility of biodegradable polyurethane (PU) foam for closure of oroantral communications (OACs).
Ten consecutive patients with OACs (existing <24 hours) were treated with PU foam. Standardized evaluations were performed at 2 weeks and 8 weeks after closure of the OAC.
In 5 patients, the OACs were closed successfully without complications. Three patients developed sinusitis, which was conservatively managed with antibiotics in 2 cases. In 1 case the sinus was reopened for irrigation, after which a buccal flap procedure was performed. In 2 patients the OAC recurred and was surgically closed with a buccal flap after thorough irrigation.
In this feasibility study, closure was achieved in 7 of the 10 patients without further surgical intervention. Complications of the procedure using PU foam may be related to the fit of the foam in the socket and the size of the perforation. In general, closure of OACs with biodegradable polyurethane foam is feasible and has the potential to spare a large number of patients with OACs a surgical procedure. Furthermore, in case the treatment with PU foam fails to close the OAC, the attending physician can always fall back on the standard surgical procedure.
本研究旨在评估可生物降解聚氨酯（PU）泡沫用于封闭口腔上颌窦交通口（OAC）的可行性。
连续10例患有OAC（病程<24小时）的患者接受了PU泡沫治疗。在封闭OAC后的2周和8周进行标准化评估。
5例患者的OAC成功封闭，无并发症发生。3例患者发生鼻窦炎，其中2例采用抗生素保守治疗。1例患者的鼻窦重新开放进行冲洗，之后进行了颊瓣手术。2例患者的OAC复发，在彻底冲洗后通过颊瓣手术进行手术封闭。
在这项可行性研究中，10例患者中有7例在无需进一步手术干预的情况下实现了封闭。使用PU泡沫进行该操作的并发症可能与泡沫在牙槽窝中的贴合情况以及穿孔大小有关。总体而言，用可生物降解聚氨酯泡沫封闭OAC是可行的，并且有可能使大量患有OAC的患者免于手术。此外，如果用PU泡沫治疗未能封闭OAC，主治医生总是可以采用标准的手术方法。
