Olmos M, Martínez A, Raffo C, Valdez I, Mendelluk G, Orcinoli M T, Magnanini F
División de Gastroenterología, Hospital Municipal Juan A. Fernández,Capital Federal, Argentina.
Acta Gastroenterol Latinoam. 1990;20(3):145-58.
In order to separate malignancy from chronic liver disease, the ascitic fluid (AF) of 45 in-patients was studied prospectively. Protein, cholesterol, triglycerides, LDH and glucose concentrations were determined in AF. Ascites/Serum (A/S) protein and LDH ratios were also established. Spontaneous bacterial peritonitis (SBP) incidence was studied in the cirrhotic group performing the pH, PMN count and culture of the AF. The 45 patients were classified in three groups: 29 with chronic liver disease, 10 with malignancy and 6 with miscellaneous pathology. Af protein concentration, its A/S ratio and AF cholesterol concentration were statistically significant (p less than 0.001) to differentiate malignancy from chronic liver disease. However, the AF glucose, triglycerides and LDH concentrations and the A/S LSH ratio were not useful in the differential diagnosis. The SBP incidence was 13%, its mortality rate 75% and the cultures were positive only in 25%.
为了区分恶性肿瘤与慢性肝病，对45例住院患者的腹水（AF）进行了前瞻性研究。测定了腹水中蛋白质、胆固醇、甘油三酯、乳酸脱氢酶（LDH）和葡萄糖的浓度。还计算了腹水/血清（A/S）蛋白和LDH比值。通过检测肝硬化组腹水的pH值、多形核白细胞（PMN）计数及培养，研究自发性细菌性腹膜炎（SBP）的发生率。45例患者分为三组：29例患有慢性肝病，10例患有恶性肿瘤，6例患有其他疾病。腹水蛋白浓度、其A/S比值及腹水胆固醇浓度在区分恶性肿瘤与慢性肝病方面具有统计学意义（p<0.001）。然而，腹水葡萄糖、甘油三酯和LDH浓度以及A/S LSH比值在鉴别诊断中并无帮助。SBP发生率为13%，死亡率为75%，培养结果仅25%呈阳性。
