参与囊泡运输的 GTPases：结构与机制。
GTPases involved in vesicular trafficking: structures and mechanisms.
机构信息
Department of Physical Biochemistry, Max-Planck-Institute of Molecular Physiology, Dortmund, Germany.
出版信息
Semin Cell Dev Biol. 2011 Feb;22(1):48-56. doi: 10.1016/j.semcdb.2010.10.003. Epub 2010 Oct 15.
PMID:20951823
Abstract
Several types of GTPases play important roles in intracellular vesicular transport. These include the Rab and Arf families of the Ras superfamily, which are key regulators of several steps in the overall process. The basic structural and mechanistic properties of these proteins and their interactions with partner proteins and membranes are reviewed and compared in this article.
摘要
几种 GTPases 在细胞内囊泡运输中发挥重要作用。这些 GTPases 包括 Ras 超家族的 Rab 和 Arf 家族，它们是整个过程中几个步骤的关键调节剂。本文综述并比较了这些蛋白质的基本结构和机械特性及其与伴侣蛋白和膜的相互作用。
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