Division of Endocrine Surgery, Department of Surgery, Università Cattolica del Sacro Cuore-Policlinico "A. Gemelli", L.go A. Gemelli 8, 00168 Rome, Italy.
J Oncol. 2010;2010. doi: 10.1155/2010/148542. Epub 2010 Sep 23.
Background. The results of video-assisted thyroidectomy (VAT) were evaluated in a large series of patients with papillary thyroid carcinoma (PTC), especially in terms of completeness of the surgical resection and short-to-medium term recurrence. Methods. The medical records of all patients who underwent video-assisted thyroidectomy for PTC between June 1998 and May 2009 were reviewed. Results. Three hundred fifty-nine patients were included. One hundred twenty-six patients underwent concomitant central neck node removal. Final histology showed 285 pT1, 26 pT2, and 48 pT3 PTC. Lymph node metastases were found in 27 cases. Follow-up was completed in 315 patients. Mean postoperative serum thyroglobulin level off levothyroxine was 5.4 ng/mL. Post operative ultrasonography showed no residual thyroid tissue in all the patients. Mean post-operative (131)I uptake was 1.7%. One patient developed lateral neck recurrence. No other recurrence was observed.
本研究评估了大样本量甲状腺乳头状癌(PTC)患者行视频辅助甲状腺切除术(VAT)的结果,尤其关注手术切除的完整性和中短期复发情况。
回顾了 1998 年 6 月至 2009 年 5 月期间所有因 PTC 行 VAT 的患者的病历资料。
共纳入 359 例患者。126 例行中央区淋巴结清扫术。术后组织病理学检查示 285 例 pT1、26 例 pT2 和 48 例 pT3 PTC。27 例发现淋巴结转移。315 例患者完成了随访。术后停用左甲状腺素钠后平均血清甲状腺球蛋白水平为 5.4ng/mL。术后所有患者的超声检查均未见甲状腺组织残留。术后(131)I 摄取平均为 1.7%。1 例患者发生侧颈部复发,无其他复发。