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孤立性纤维瘤:胸膜外表现谱的最新研究进展。

Solitary fibrous tumor: an update on the spectrum of extrapleural manifestations.

机构信息

Department of Radiology, McGill University Health Centre, Montreal General Hospital, 1650 Avenue Cedar, C5-118, Montréal, Québec, H3G 1A4, Canada.

出版信息

Skeletal Radiol. 2012 Jan;41(1):5-13. doi: 10.1007/s00256-010-1032-z. Epub 2010 Oct 16.

Abstract

Solitary fibrous tumor (SFT) is a rare tumor initially believed to be a benign localized pleural tumor of mesothelial origin. Over the past few years, the literature on this tumor has grown tremendously. The tumor is now reported in diverse bodily locations, and recognized to have a wider range of clinical and radiological features. The most common extrapleural sites of the tumor are the orbits and the extremities. Tumors are often well-circumscribed masses, and vary in size from 1 cm to over 30 cm. The admixture of histological components in the tumor, namely, fibrous tissue, cellular components, and highly vascularized areas consisting of numerous closely packed small to medium-sized blood vessels, influence the imaging appearances of the tumor. On magnetic resonance imaging (MRI), the diagnosis of solitary fibrous tumor is suggested by a well-circumscribed mass that has smooth margins, and focal or diffuse hypointense signal on T2-weighted imaging due to fibrous content in the tumor. SFTs demonstrate strong focal or diffuse contrast enhancement due to the highly vascularized areas in the tumor.

摘要

孤立性纤维瘤(SFT)是一种罕见的肿瘤,最初被认为是一种良性局限性间皮起源的胸膜肿瘤。在过去的几年中,关于这种肿瘤的文献大量增加。该肿瘤现在已在不同的身体部位报道,并被认为具有更广泛的临床和影像学特征。肿瘤最常见的胸膜外部位是眼眶和四肢。肿瘤通常是边界清楚的肿块,大小从 1 厘米到 30 厘米以上不等。肿瘤中组织学成分的混合,即纤维组织、细胞成分和富含血管的区域,由许多紧密堆积的小到中等大小的血管组成,影响了肿瘤的影像学表现。在磁共振成像(MRI)上,孤立性纤维瘤的诊断提示为边界清楚的肿块,边缘光滑,由于肿瘤中的纤维含量,T2 加权成像上呈局灶性或弥漫性低信号。由于肿瘤中富含血管的区域,SFT 表现为强烈的局灶性或弥漫性对比增强。

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