Neurol Sci. 2011 Jun;32(3):381-5. doi: 10.1007/s10072-010-0434-y. Epub 2010 Oct 16.
Guillain-Barré syndrome (GBS) is one of the reasons of acute polyneuropathy causing severe morbidity and mortality. Forty-six patients with GBS were included in our study. Clinical, laboratory, electrophysiological and prognostic features of the patients were evaluated retrospectively. Patients were divided into two groups. Group A consisted of children who attained a full recovery within 2 months from onset of the disease; group B consisted of children who experienced complete or partial recovery beyond 2 months from onset of the disease. Acute inflammatory demyelinating polyradiculoneuropathy was found in 56.5% of patients and axonal form in 43.5% patients. Antecedent events were found in 28 (60.9%) patients. Five patients (10.8%) needed mechanical ventilation and one patient (2.1%) died. Poor outcome was related with clinic stage and electrophysiological subtypes (axonal form). In our study, poor prognostic factors were related with clinic stage and electrophysiological subtypes (axonal form).
格林-巴利综合征(GBS)是导致严重发病率和死亡率的急性多发性神经病的原因之一。我们的研究纳入了 46 例 GBS 患者。回顾性评估了患者的临床、实验室、电生理和预后特征。患者分为两组。A 组包括在发病后 2 个月内完全康复的儿童;B 组包括在发病后 2 个月以上完全或部分康复的儿童。56.5%的患者为急性炎症性脱髓鞘性多发性神经根神经病,43.5%的患者为轴索性。28 例(60.9%)患者有前驱事件。5 例(10.8%)患者需要机械通气,1 例(2.1%)患者死亡。不良预后与临床分期和电生理亚型(轴索性)有关。在我们的研究中,不良预后因素与临床分期和电生理亚型(轴索性)有关。