Patel Nandesh N, Shulman Julia P, Chin Kimberly J, Finger Paul T
The New York Eye Cancer Center, New York, NY, USA.
Ophthalmic Surg Lasers Imaging. 2010 Nov-Dec;41(6):614-21. doi: 10.3928/15428877-20100929-07. Epub 2010 Sep 29.
To evaluate optical coherence tomography/scanning laser ophthalmoscopy (OCT/SLO) imaging for optic nerve head drusen (ONHD).
Nine consecutive eyes with ONHD were imaged. Each underwent visual field testing, 20-MHz B-scan ultrasonography, photography, and OCT/SLO imaging of the nerve head. Similar evaluation was performed on 12 matched, disease-free control eyes for comparison.
OCT/SLO imaging of ONHD demonstrated lucencies (100%), variable amounts of displacement, and thickening of the overlying nerve fiber layer, as well as disorganization of the adjacent retinal pigment epithelium (44%). Optic nerve head topography was measured (using horizontal and vertical electronic calipers). Mean disc diameter was 1.81 mm (range: 1.49 to 2.12 mm). All ONHD demonstrated anterior displacement of the base of the optic nerve cup (shallowing) compared to controls. The cup base was a mean +0.32 mm anterior to the retinal pigment epithelium for ONHD versus -0.23 mm for normal controls.
OCT/SLO revealed unique and clinically helpful views of ONHD.
评估光学相干断层扫描/扫描激光检眼镜(OCT/SLO)对视乳头 drusen(ONHD)的成像情况。
对连续9只患有ONHD的眼睛进行成像。每只眼睛均接受了视野测试、20兆赫兹B扫描超声检查、摄影以及对视乳头的OCT/SLO成像。对12只匹配的无疾病对照眼进行了类似评估以作比较。
ONHD的OCT/SLO成像显示有透亮区(100%)、不同程度的移位、上方神经纤维层增厚,以及相邻视网膜色素上皮紊乱(44%)。测量了视乳头地形图(使用水平和垂直电子卡尺)。平均视盘直径为1.81毫米(范围:1.49至2.12毫米)。与对照组相比,所有ONHD均显示视神经杯底部向前移位(变浅)。ONHD的杯底部平均位于视网膜色素上皮前方+0.32毫米处,而正常对照组为-0.23毫米。
OCT/SLO揭示了ONHD独特且对临床有帮助的图像。