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脱矿骨锯末在脊柱损伤治疗中的应用

[Use of demineralized bone sawdust in the treatment of spinal injuries].

作者信息

Shvets A I, Fadeev G I

出版信息

Ortop Travmatol Protez. 1990 Nov(11):22-3.

PMID:2095490
Abstract

The experimental investigation for the purpose of studying the possibility of intervertebral osseous adhesion formation when demineralized osseous sawdust is introduced in the intervertebral disk in case of penetrating fractures of bodies of vertebra has been carried out. In 70% of cases the osseous adhesion is formed at the level of disks which demineralized osseous sawdust was introduced to (adhesion was formed, mainly, as perifocal osseous stratifications). Osseous adhesion, in case of introduction of lekozim to the damaged disk, was noted in 20% of cases (1 animal). Osteogenesis in disks was absent in all observations in the control group. When used in clinics in 12 patients with injuries of vertebral column in 63.6% of them perivertebral osseous connection has been formed during 8-12 months.

摘要

为研究在椎体穿透性骨折时将脱矿骨屑引入椎间盘后形成椎间骨粘连的可能性,已开展了实验研究。在70%的病例中,在引入脱矿骨屑的椎间盘水平形成了骨粘连(粘连主要表现为灶周骨分层)。在20%的病例(1只动物)中,当向受损椎间盘引入lekozim时,观察到骨粘连。对照组的所有观察结果中,椎间盘均未发生骨生成。在临床上,12例脊柱损伤患者中,63.6%的患者在8 - 12个月内形成了椎周骨连接。

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