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体位性与非体位性阻塞性睡眠呼吸暂停患者:一项关于与呼吸暂停低通气严重程度相关危险因素的回顾性研究

Patients with positional versus nonpositional obstructive sleep apnea: a retrospective study of risk factors associated with apnea-hypopnea severity.

作者信息

Chung Jin Woo, Enciso Reyes, Levendowski Daniel J, Westbrook Philip R, Clark Glenn T

机构信息

Department of Oral Medicine and Oral Diagnosis, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Korea.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Nov;110(5):605-10. doi: 10.1016/j.tripleo.2010.06.017.

DOI:10.1016/j.tripleo.2010.06.017
PMID:20955950
Abstract

OBJECTIVE

The aim of this study was to investigate the differences in and risk factors for positional and nonpositional obstructive sleep apnea (OSA).

STUDY DESIGN

One hundred twenty-three nonpositional (supine apnea-hypopnea index [AHI] < 2 times the lateral AHI), 218 positional (supine AHI ≥ 2 times the lateral AHI), and 109 age-, gender-, and BMI-matched patients with positional OSA performed 2 nights of sleep study. Gender, age, BMI, and percentage of time in supine position, and percentage of time snoring louder than 40 dB were evaluated as risk factors.

RESULTS

Both unmatched positional and matched positional patients had less severe overall AHI values, higher mean SpO(2), lower percentage time SpO(2) less than 90%, and lower percentage of time snoring when compared with the nonpositional group. Overall AHI scores were associated with increasing age and percentage of time snoring for positional and nonpositional groups. However, BMIs were associated with the overall AHI only in the nonpositional group.

CONCLUSION

The influence of position on OSA severity may contribute to the choice and prognosis of treatment and may represent 2 distinct groups with probable anatomic differences.

摘要

目的

本研究旨在调查体位性和非体位性阻塞性睡眠呼吸暂停(OSA)的差异及危险因素。

研究设计

123例非体位性患者(仰卧位呼吸暂停低通气指数[AHI]<侧卧位AHI的2倍)、218例体位性患者(仰卧位AHI≥侧卧位AHI的2倍)以及109例年龄、性别和BMI匹配的体位性OSA患者进行了两晚的睡眠研究。将性别、年龄、BMI、仰卧位时间百分比以及鼾声大于40dB的时间百分比评估为危险因素。

结果

与非体位性组相比,未匹配的体位性患者和匹配的体位性患者总体AHI值均较轻,平均SpO₂较高,SpO₂低于90%的时间百分比较低,打鼾时间百分比也较低。体位性和非体位性组的总体AHI评分均与年龄增长和打鼾时间百分比增加相关。然而,BMI仅与非体位性组的总体AHI相关。

结论

体位对OSA严重程度的影响可能有助于治疗的选择和预后,可能代表两个具有解剖学差异的不同组。

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