Ganz Patricia A
Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center, 650 Charles Young Dr South, Rm A2-125 CHS, Los Angeles, CA 90095-6900, USA.
J Natl Cancer Inst Monogr. 2010;2010(41):218-22. doi: 10.1093/jncimonographs/lgq029.
Ductal carcinoma in situ (DCIS) as we know it today is a clinical entity that is primarily discovered through the finding of microscopic calcifications on a screening mammogram. Asymptomatic women who are found to have DCIS receive treatments that are similar to women with invasive breast cancer and experience substantial psychological distress in spite of having an excellent prognosis and normal life expectancy. More research is needed to determine the best way to communicate with women about this condition and to match the extent of treatment with the risk of serious future disease. Clinical and research efforts should focus on reducing the anxiety and psychological distress associated with the diagnosis of DCIS.
我们如今所熟知的导管原位癌(DCIS)是一种临床实体,主要通过筛查乳房X光片上发现的微小钙化来确诊。被发现患有DCIS的无症状女性接受的治疗与浸润性乳腺癌女性相似,尽管预后良好且预期寿命正常,但她们仍会经历严重的心理困扰。需要更多研究来确定与女性沟通这种疾病的最佳方式,并使治疗程度与未来患严重疾病的风险相匹配。临床和研究工作应专注于减轻与DCIS诊断相关的焦虑和心理困扰。