Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.
CA Cancer J Clin. 2010 Nov-Dec;60(6):351-75. doi: 10.3322/caac.20082. Epub 2010 Oct 19.
Inflammatory breast cancer (IBC) is a rare and aggressive form of invasive breast cancer accounting for 2.5% of all breast cancer cases. It is characterized by rapid progression, local and distant metastases, younger age of onset, and lower overall survival compared with other breast cancers. Historically, IBC is a lethal disease with less than a 5% survival rate beyond 5 years when treated with surgery or radiation therapy. Because of its rarity, IBC is often misdiagnosed as mastitis or generalized dermatitis. This review examines IBC's unique clinical presentation, pathology, epidemiology, imaging, and biology and details current multidisciplinary management of the disease, which comprises systemic therapy, surgery, and radiation therapy.
炎性乳腺癌（IBC）是一种罕见且侵袭性的浸润性乳腺癌，占所有乳腺癌病例的 2.5%。与其他乳腺癌相比，它的特点是进展迅速、局部和远处转移、发病年龄较轻以及整体生存率较低。从历史上看，IBC 是一种致命疾病，采用手术或放射疗法治疗时，5 年生存率低于 5%。由于其罕见性，IBC 常被误诊为乳腺炎或全身性皮炎。本综述检查了 IBC 的独特临床表现、病理学、流行病学、影像学和生物学，并详细介绍了该病目前的多学科管理，包括系统治疗、手术和放射治疗。
