From the Division of Breast Imaging, Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, RA Bldg, RA-014, Boston, MA 02115 (E.D.Y., R.L.B., D.G.S., C.S.G.); and Department of Imaging (H.A.J., A.D.V.d.A.), Department of Radiation Oncology (J.R.B.), Department of Surgery (F.N.), Department of Breast Oncology (B.O.), and Inflammatory Breast Cancer Program (E.D.Y., H.A.J., J.R.B., F.N., J.H.B., B.O.), Dana-Farber Cancer Institute, Boston, Mass.
Radiographics. 2013 Nov-Dec;33(7):2003-17. doi: 10.1148/rg.337135503.
Inflammatory breast cancer (IBC) is a rare breast cancer with a highly virulent course and low 5-year survival rate. Trimodality treatment that includes preoperative chemotherapy, mastectomy, and radiation therapy is the therapeutic mainstay and has been shown to improve prognosis. Proper diagnosis and staging of IBC is critical to treatment planning and requires a multidisciplinary approach that includes imaging. Patients with IBC typically present with rapid onset of breast erythema, edema, and peau d'orange. Both tissue diagnosis of malignancy and clinical findings of inflammatory disease are required to confirm diagnosis of IBC. Imaging is used to identify a biopsy target; direct biopsy; stage IBC; differentiate curable from incurable (stage IV) disease; and help plan chemotherapy, surgical management, and radiation therapy. Comparison of baseline and posttreatment images helps confirm and quantitate disease response. When imaging is used early in the course of therapy to noninvasively predict treatment response, optimal tailored strategies for management of IBC can be implemented. Imaging is vital to diagnosis and treatment planning for patients with IBC, and radiologists are an integral part of the multidisciplinary patient care team.
炎性乳腺癌（IBC）是一种罕见的乳腺癌，具有高度侵袭性病程和低 5 年生存率。包括术前化疗、乳房切除术和放射治疗的三联疗法是主要治疗方法，已被证明可改善预后。正确的 IBC 诊断和分期对于治疗计划至关重要，需要多学科方法，包括影像学。IBC 患者通常表现为乳房红斑、水肿和橘皮样变的快速发作。需要组织学诊断恶性肿瘤和临床炎症性疾病的表现来确诊 IBC。影像学用于确定活检靶标；直接活检；IBC 分期；区分可治愈（IV 期）与不可治愈疾病；并帮助规划化疗、手术管理和放射治疗。比较基线和治疗后图像有助于确认和量化疾病反应。当在治疗过程早期使用影像学来非侵入性地预测治疗反应时，可以实施针对 IBC 管理的最佳定制策略。影像学对于 IBC 患者的诊断和治疗计划至关重要，放射科医生是多学科患者护理团队的重要组成部分。
