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本文引用的文献

1
Adverse events associated with testosterone administration.与睾酮治疗相关的不良反应。
N Engl J Med. 2010 Jul 8;363(2):109-22. doi: 10.1056/NEJMoa1000485. Epub 2010 Jun 30.
2
Identification of late-onset hypogonadism in middle-aged and elderly men.中老年男性迟发性性腺功能减退症的识别。
N Engl J Med. 2010 Jul 8;363(2):123-35. doi: 10.1056/NEJMoa0911101. Epub 2010 Jun 16.
3
Clinical review 1: Adverse effects of testosterone therapy in adult men: a systematic review and meta-analysis.临床综述 1:雄激素治疗对成年男性的不良反应:系统评价和荟萃分析。
J Clin Endocrinol Metab. 2010 Jun;95(6):2560-75. doi: 10.1210/jc.2009-2575.
4
Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline.男性雄激素缺乏综合征的睾酮治疗:内分泌学会临床实践指南。
J Clin Endocrinol Metab. 2010 Jun;95(6):2536-59. doi: 10.1210/jc.2009-2354.
5
Prevalence and incidence of androgen deficiency in middle-aged and older men: estimates from the Massachusetts Male Aging Study.中老年男性雄激素缺乏的患病率和发病率:来自马萨诸塞州男性衰老研究的估计
J Clin Endocrinol Metab. 2004 Dec;89(12):5920-6. doi: 10.1210/jc.2003-031719.
6
Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscle.老年男性与年轻男性一样,对不同剂量睾酮对骨骼肌的合成代谢作用有相同的反应。
J Clin Endocrinol Metab. 2005 Feb;90(2):678-88. doi: 10.1210/jc.2004-1184. Epub 2004 Nov 23.
7
Measurement of total serum testosterone in adult men: comparison of current laboratory methods versus liquid chromatography-tandem mass spectrometry.成年男性血清总睾酮的测定:当前实验室方法与液相色谱-串联质谱法的比较
J Clin Endocrinol Metab. 2004 Feb;89(2):534-43. doi: 10.1210/jc.2003-031287.
8
Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging.衰老对健康男性血清总睾酮和游离睾酮水平的纵向影响。巴尔的摩衰老纵向研究。
J Clin Endocrinol Metab. 2001 Feb;86(2):724-31. doi: 10.1210/jcem.86.2.7219.
9
Health status in VA patients: results from the Veterans Health Study.退伍军人事务部患者的健康状况:退伍军人健康研究结果
Am J Med Qual. 1999 Jan-Feb;14(1):28-38. doi: 10.1177/106286069901400105.

生殖内分泌学:迟发性性腺功能减退症:诊断标准的证据。

Reproductive endocrinology: Late-onset hypogonadism: evidence for diagnostic criteria.

机构信息

Department of Medicine, University of Washington School of Medicine, 1959 Northeast Pacific Street, Seattle, WA 98195-7138, USA.

出版信息

Nat Rev Endocrinol. 2010 Nov;6(11):602-3. doi: 10.1038/nrendo.2010.154.

DOI:10.1038/nrendo.2010.154
PMID:20962865
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3686492/
Abstract

Various symptoms are typical of severe testosterone deficiency in young men; in aging men, however, these symptoms are nonspecific and overlap with symptoms of other prevalent disorders. A new study offers evidence-based criteria for the identification of late-onset hypogonadism in the general population on the basis of an association between symptoms and a low testosterone level.

摘要

各种症状是年轻男性严重睾酮缺乏的典型表现;然而,在老年男性中,这些症状是非特异性的,与其他常见疾病的症状相重叠。一项新的研究基于症状与低睾酮水平之间的关联,为一般人群中迟发性性腺功能减退症的识别提供了基于证据的标准。