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八旬老人冠状动脉搭桥术:长期结果

Coronary artery bypass grafting in octogenarians: long-term results.

作者信息

Serrão Marco, Graça Francisco, Rodrigues Rui, Abecasis Miguel, Bruges Luís, Calquinha José, Neves José, Bebocho Maria José, Ferreira Moradas, Queiroz e Melo J

机构信息

Serviço de Cirurgia Cardiotorácica, Hospital de Santa Cruz, Lisboa, Portugal.

出版信息

Rev Port Cardiol. 2010 Jun;29(6):989-98.

Abstract

INTRODUCTION

As surgical revascularization is becoming more frequent in octogenarians, we reviewed our data to analyze the impact of coronary artery bypass grafting on short- and long-term morbidity and mortality.

METHODS

We performed a retrospective study of 101 consecutive patients aged 80 years or older, who underwent coronary artery bypass in a single cardiac center between January 2002 and December 2007. The patients were divided into two groups: off-pump (64.4%) and on-pump (35.6%), depending on whether the surgery was performed with cardiopulmonary bypass. Early results and those up to 6 years after surgery were assessed.

RESULTS

Baseline characteristics were similar between the groups and follow-up was 90% complete. There were no significant differences between groups in mean age (off-pump = 82.7 +/- 18 years vs. on-pump = 82.2 +/- 2.2 years; p = NS) or in logistic EuroSCORE (off-pump = 11.2 +/- 12.3 vs. on-pump = 8.5 +/- 5.1; p = NS). However, the off-pump group had less complete revascularization (off-pump = 43.1% vs. on-pump = 83.3%, p = 0.0001) and shorter mean hospital stay (off-pump = 9.3 +/- 5.4 days vs. on-pump = 11.5 +/- 7.3 days; p = 0.09). Both groups showed low hospital mortality (off-pump = 1.5% vs. on-pump = 2.8%, p = NS). At 6-year follow-up, off-pump surgery patients had the same late prognosis (total survival: off-pump = 80% vs. on-pump = 77.4%, p = NS; cardiovascular mortality: off-pump = 15% vs. on-pump = 16.1%, p = NS).

CONCLUSION

In octogenarians coronary artery bypass grafting had excellent results. The off-pump technique, even though it can mean less complete revascularization, leads to shorter hospital stay and has the same 6-year results as in patients operated under cardiopulmonary bypass.

摘要

引言

随着手术血管重建术在八旬老人中越来越频繁,我们回顾了我们的数据,以分析冠状动脉搭桥术对短期和长期发病率及死亡率的影响。

方法

我们对2002年1月至2007年12月期间在单一心脏中心接受冠状动脉搭桥术的101例连续80岁及以上患者进行了回顾性研究。根据手术是否在体外循环下进行,将患者分为两组:非体外循环组(64.4%)和体外循环组(35.6%)。评估早期结果以及术后6年的结果。

结果

两组的基线特征相似,随访完成率为90%。两组在平均年龄(非体外循环组=82.7±1.8岁,体外循环组=82.2±2.2岁;p=无统计学意义)或逻辑欧洲心脏手术风险评估系统评分(非体外循环组=11.2±12.3,体外循环组=8.5±5.1;p=无统计学意义)方面无显著差异。然而,非体外循环组的血管重建不完全率较低(非体外循环组=43.1%,体外循环组=83.3%,p=0.0001),平均住院时间较短(非体外循环组=9.3±5.4天,体外循环组=11.5±7.3天;p=0.09)。两组的住院死亡率均较低(非体外循环组=1.5%,体外循环组=2.8%,p=无统计学意义)。在6年随访时,非体外循环手术患者的晚期预后相同(总生存率:非体外循环组=80%,体外循环组=77.4%,p=无统计学意义;心血管死亡率:非体外循环组=15%,体外循环组=16.1%,p=无统计学意义)。

结论

在八旬老人中,冠状动脉搭桥术取得了优异的结果。非体外循环技术尽管可能意味着血管重建不完全,但可缩短住院时间,并且6年结果与在体外循环下手术的患者相同。

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