Suppr超能文献

[特纳综合征与自身免疫性甲状腺功能减退症]

[Turner's syndrome and autoimmune dysthyroidism].

作者信息

Ortéga F, Guérin V, Créa T, Hartemann P

机构信息

Service d'Endocrinologie, CHU, Nancy.

出版信息

Rev Med Interne. 1990 Jul-Aug;11(4):333-5. doi: 10.1016/s0248-8663(05)80870-7.

Abstract

The authors report a case of Turner's syndrome associated with Hashimoto's thyroiditis and present the various physiopathological hypotheses currently offered to explain the frequent association of an autoimmune pathology and a gonadal dysgenesis with an absence of X chromosome which is held responsible for autoimmunity. Is the chromosomal abnormality a factor predisposing to autoimmunity or does it result from a disturbance of the immune mechanism? Environmental factors, such as bacteria, viruses or some pollutants might be responsible for both the immune disorders and the chromosomal abnormality. The association of the two types of disease may also be accidental. In the present state of our knowledge, there is no answer to these questions.

摘要

作者报告了一例特纳综合征合并桥本甲状腺炎的病例,并提出了目前用于解释自身免疫性疾病与性腺发育不全频繁关联的各种生理病理假说,这种关联与认为是自身免疫性疾病病因的X染色体缺失有关。染色体异常是自身免疫的易感因素,还是免疫机制紊乱的结果?环境因素,如细菌、病毒或某些污染物,可能是免疫紊乱和染色体异常的原因。这两种疾病的关联也可能是偶然的。就我们目前的知识水平而言,这些问题尚无答案。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验