Centre for Biomedical Imaging, Université de Lausanne, Lausanne, Switzerland.
Neuroimage. 2011 Feb 1;54(3):1803-11. doi: 10.1016/j.neuroimage.2010.10.032. Epub 2010 Oct 18.
Evidence from human and non-human primate studies supports a dual-pathway model of audition, with partially segregated cortical networks for sound recognition and sound localisation, referred to as the What and Where processing streams. In normal subjects, these two networks overlap partially on the supra-temporal plane, suggesting that some early-stage auditory areas are involved in processing of either auditory feature alone or of both. Using high-resolution 7-T fMRI we have investigated the influence of positional information on sound object representations by comparing activation patterns to environmental sounds lateralised to the right or left ear. While unilaterally presented sounds induced bilateral activation, small clusters in specific non-primary auditory areas were significantly more activated by contra-laterally presented stimuli. Comparison of these data with histologically identified non-primary auditory areas suggests that the coding of sound objects within early-stage auditory areas lateral and posterior to primary auditory cortex AI is modulated by the position of the sound, while that within anterior areas is not.
来自人类和非人类灵长类动物研究的证据支持听觉的双通道模型，其中包括用于声音识别和声音定位的部分分离的皮质网络，称为“什么”和“哪里”处理流。在正常受试者中，这两个网络在颞上平面上部分重叠，表明一些早期听觉区域单独参与处理听觉特征，或者同时参与处理两种听觉特征。我们使用高分辨率 7-T fMRI 通过比较对右侧或左侧耳呈现的环境声音的激活模式，研究了位置信息对声音对象表示的影响。虽然单侧呈现的声音会引起双侧激活，但特定非主要听觉区域中的小簇在对侧呈现的刺激下明显更活跃。将这些数据与组织学上确定的非主要听觉区域进行比较表明，在初级听觉皮层 AI 外侧和后部的早期听觉区域内，声音对象的编码受到声音位置的调制，而在前部区域内则不受调制。
