Department of Medicine, Columbia University, New York, NY 10032, USA.
J Thorac Cardiovasc Surg. 2011 Jul;142(1):73-6. doi: 10.1016/j.jtcvs.2010.08.028. Epub 2010 Oct 20.
Temporary biventricular pacing to treat low output states after cardiac surgery is an active area of investigation. Reoperative cases are not studied due to adhesions, which preclude left ventricular mobilization to place epicardial pacing wires. In such patients, inserting a temporary left ventricular lead via the coronary sinus cardioplegia cannula may allow for biventricular pacing. We developed a novel technique for intraoperative left ventricular lead placement.
Eight domestic pigs underwent median sternotomy and pericardiotomy. Temporary pacing wires were sewn to the right atrium and right ventricle. Complete heart block was induced by ethanol ablation of the atrioventricular node. A 13-French retrograde cardioplegia catheter was introduced via the right atrial free wall into the coronary sinus. A 6-French left ventricular pacing lead was inserted into the cardioplegia catheter and advanced into the coronary sinus during biventricular pacing until left ventricular capture was detected by electrocardiogram and arterial pressure monitoring. Left ventricular capture success rate and electrical performance were recorded during five placement attempts.
Left ventricular capture was achieved on 80% of insertion attempts. Left ventricular capture without diaphragmatic pacing was achieved in 7 pigs. Lead tip locations were mostly in lateral and posterior basal coronary vein branches. There were no arrhythmias, bleeding, or perforation associated with lead insertion.
Intraoperative biventricular pacing with a left ventricular pacing lead inserted via the coronary sinus cardioplegia cannula is feasible, using standard instrumentation and without requiring cardiac manipulation. This approach merits further study in patients undergoing reoperative cardiac surgery.
心脏手术后治疗低心排血量的临时双心室起搏是一个活跃的研究领域。由于粘连,无法进行左心室游离以放置心外膜起搏导线,因此不研究再次手术的病例。在这些患者中,通过冠状静脉窦心肌保护套管插入临时左心室导联可能允许进行双心室起搏。我们开发了一种用于术中左心室导联放置的新方法。
八只家猪进行正中胸骨切开术和心包切开术。将临时起搏导线缝到右心房和右心室。通过乙醇消融房室结诱导完全性心脏阻滞。通过右心房游离壁将 13 号逆行心肌保护导管引入冠状窦。将 6 号左心室起搏导联插入心肌保护导管,并在双心室起搏期间推进到冠状窦,直到心电图和动脉压监测检测到左心室捕获。在五次放置尝试中记录左心室捕获成功率和电性能。
80%的插入尝试中实现了左心室捕获。在 7 只猪中实现了无膈肌起搏的左心室捕获。导联尖端位置主要在侧和后基底冠状静脉分支。没有与导联插入相关的心律失常、出血或穿孔。
使用标准仪器且无需心脏操作,通过冠状静脉窦心肌保护套管插入左心室起搏导联进行术中双心室起搏是可行的。这种方法值得在接受再次心脏手术的患者中进一步研究。