Cheng Chao, Long Xiao bin
Department of Otorhinolaryngology-Head and Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2010 Oct;30(10):2402-3, 2405.
To discuss the clinical characteristics, diagnosis and treatment of esthesioneuroblastoma (ENB).
The clinical data of 7 patients with ENB were analyzed retrospectively, and the clinical characteristics, diagnosis, surgical approaches and prognosis of the disease were discussed.
The 7 patients received surgical treatment combined with radiotherapy and chemotherapy. Tumor relapse occurred within one year in two cases, which were treated with a second operation combined with radiotherapy, and one patient died and one survived with tumor after a one-year follow-up.
Early diagnosis of ENB can be difficult. Transnasal-frontal approach with nasal endoscope is effective approach to ENB treatment, and the patients may benefit from postoperative radiotherapy and chemotherapy to improve the prognosis.
探讨嗅神经母细胞瘤（ENB）的临床特征、诊断及治疗方法。
回顾性分析7例ENB患者的临床资料，探讨该病的临床特征、诊断、手术方式及预后。
7例患者均接受了手术治疗并联合放化疗。2例患者在1年内出现肿瘤复发，接受了二次手术并联合放疗，1例患者死亡，1例患者随访1年后带瘤生存。
ENB早期诊断可能困难。鼻内镜经鼻-额入路是治疗ENB的有效方法，患者术后接受放化疗可能有助于改善预后。
