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3DID：已知三维结构的基于结构域的相互作用的识别与分类

3did: identification and classification of domain-based interactions of known three-dimensional structure.

作者信息

Stein Amelie, Céol Arnaud, Aloy Patrick

机构信息

Institute for Research in Biomedicine, Join IRB-BSC Program in Computational Biology, 08028 Barcelona, Spain.

出版信息

Nucleic Acids Res. 2011 Jan;39(Database issue):D718-23. doi: 10.1093/nar/gkq962. Epub 2010 Oct 21.

DOI:10.1093/nar/gkq962
PMID:20965963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3013799/
Abstract

The database of three-dimensional interacting domains (3did) is a collection of protein interactions for which high-resolution three-dimensional structures are known. 3did exploits the availability of structural data to provide molecular details on interactions between two globular domains as well as novel domain-peptide interactions, derived using a recently published method from our lab. The interface residues are presented for each interaction type individually, plus global domain interfaces at which one or more partners (domains or peptides) bind. The 3did web server at http://3did.irbbarcelona.org visualizes these interfaces along with atomic details of individual interactions using Jmol. The complete contents are also available for download.

摘要

三维相互作用结构域数据库（3did）是一个已知高分辨率三维结构的蛋白质相互作用集合。3did利用结构数据的可用性，提供两个球状结构域之间相互作用的分子细节以及新的结构域 - 肽相互作用，这些相互作用是使用我们实验室最近发表的方法推导出来的。针对每种相互作用类型单独呈现界面残基，以及一个或多个伙伴（结构域或肽）结合的全局结构域界面。位于http://3did.irbbarcelona.org的3did网络服务器使用Jmol可视化这些界面以及单个相互作用的原子细节。完整内容也可供下载。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b1/3013799/c03ad5436bde/gkq962f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b1/3013799/79c9828806d4/gkq962f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b1/3013799/f8e838a68127/gkq962f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b1/3013799/7ccc3ed05f35/gkq962f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b1/3013799/c03ad5436bde/gkq962f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b1/3013799/79c9828806d4/gkq962f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b1/3013799/f8e838a68127/gkq962f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b1/3013799/7ccc3ed05f35/gkq962f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b1/3013799/c03ad5436bde/gkq962f4.jpg

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