Niedźwiedzka-Rystwej Paulina, Mękal Agata, Deptuła Wiesław
Katedra Mikrobiologii i Immunologii, Wydział Nauk Przyrodniczych, Uniwersytet Szczeciński, 71-412 Szczecin.
Postepy Hig Med Dosw (Online). 2010 Aug 30;64:417-22.
Development of artherosclerosis is associated with participation of various cell types of the immune system such as: granulocytes, B and T lymphocytes, mast cells, dendritic cells and progenitor cells. Cytokines and growth factors have a great impact on activation of the atheromatous plaque. This pathological process results in increase of artery's tunic intima thickness, leading to coronary heart disease, myocardial infarction or stroke. It is suggested that a closer look at participation of the immune system cells in artherosclerosis may contribute to a change in the profile of therapy of this disease.
动脉粥样硬化的发展与免疫系统的多种细胞类型参与有关，如：粒细胞、B和T淋巴细胞、肥大细胞、树突状细胞和祖细胞。细胞因子和生长因子对动脉粥样斑块的激活有很大影响。这一病理过程导致动脉内膜厚度增加，进而引发冠心病、心肌梗死或中风。有人认为，深入研究免疫系统细胞在动脉粥样硬化中的参与情况可能有助于改变这种疾病的治疗模式。
