Bagüeste Graciella, Porcel Jose M
Internal Medicine, Arnau de Vilanova University Hospital, Lleida, ESP.
Cureus. 2021 Apr 26;13(4):e14697. doi: 10.7759/cureus.14697.
is a rare Nocardia species causing localized (lung, brain, skin) and disseminated infections. Predisposing factors include the chronic use of corticosteroids, organ transplantation and other immunocompromise conditions. Pleural empyema caused by this microorganism has scantily been reported. We describe two cases of pleural infection by that occurred in patients with a kidney transplant and cirrhosis, respectively. The first patient died soon after hospitalization, while the second survived nocardiosis (despite having significant adverse events to antibiotics) but eventually succumbed to other infectious complications. In this infectious disease, in which the duration of therapy is typically long and pleural space drainage is frequently required, bacterial susceptibility to antimicrobial agents should be tested.
是一种罕见的诺卡菌属，可引起局部（肺、脑、皮肤）和播散性感染。易感因素包括长期使用皮质类固醇、器官移植和其他免疫功能低下的情况。由这种微生物引起的胸膜脓胸鲜有报道。我们描述了分别发生在肾移植患者和肝硬化患者中的两例由该菌引起的胸膜感染病例。首例患者在住院后不久死亡，而第二例患者诺卡菌病存活（尽管对抗生素有严重不良事件），但最终死于其他感染并发症。在这种治疗疗程通常较长且常需要进行胸腔引流的传染病中，应检测细菌对抗菌药物的敏感性。
