神经性厌食症女性的意外妊娠。
Unplanned pregnancy in women with anorexia nervosa.
机构信息
Departments of Psychiatry and Nutrition, University of North Carolina, Chapel Hill, North Carolina 27599-7160, USA.
出版信息
Obstet Gynecol. 2010 Nov;116(5):1136-40. doi: 10.1097/AOG.0b013e3181f7efdc.
OBJECTIVE
To compare the frequency with which unplanned pregnancies occur in individuals with anorexia nervosa relative to women without eating disorders in the Norwegian Mother and Child Cohort Study.
METHOD
In a sample of 62,060 women, 62 reported anorexia nervosa. Using data from a questionnaire completed by all participating mothers, we compared mother's age at birth and the frequency with which mothers reported their index pregnancy as being unplanned.
RESULTS
Women with anorexia nervosa were younger (26.2 years, standard deviation 4.76) than women with no eating disorder (29.9 years, standard deviation 4.60) at the time of birth. Significantly more women with anorexia nervosa (50.0%) reported unplanned pregnancy than women in the referent group (18.9%). After adjustment for maternal age and infertility treatment, the relative risk of unplanned pregnancy in individuals with anorexia nervosa was 2.11 (95% confidence interval 1.64-2.72). Induced abortion was also significantly more common in women with anorexia nervosa than referent women (24.2% compared with 14.6%).
CONCLUSION
The higher rate of unplanned pregnancy and abortion in women with anorexia nervosa is of clinical concern because absent or irregular menstruation may be misinterpreted as decreasing risk of pregnancy.
LEVEL OF EVIDENCE
II.
目的
在挪威母亲和儿童队列研究中，比较神经性厌食症个体与无饮食障碍女性之间意外怀孕的频率。
方法
在 62060 名女性中，有 62 名报告患有神经性厌食症。利用所有参与母亲完成的问卷数据，我们比较了母亲的出生年龄和母亲报告其指数妊娠为意外妊娠的频率。
结果
在出生时，患有神经性厌食症的女性（26.2 岁，标准差 4.76）比无饮食障碍的女性（29.9 岁，标准差 4.60）年轻。报告意外怀孕的神经性厌食症女性（50.0%）明显多于参照组女性（18.9%）。调整母亲年龄和不孕治疗后，神经性厌食症个体意外怀孕的相对风险为 2.11（95%置信区间 1.64-2.72）。与参照女性相比，神经性厌食症女性的人工流产也明显更为常见（24.2%比 14.6%）。
结论
神经性厌食症女性意外怀孕和流产的比率较高，这引起了临床关注，因为不规则或无月经可能被误解为降低怀孕风险。
证据水平
II。
Zotero 插件