Diabetes Prevention Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.
Obesity (Silver Spring). 2011 Apr;19(4):848-52. doi: 10.1038/oby.2010.236. Epub 2010 Oct 21.
We evaluated how body fat percentage, measured by a portable near-infrared interactance (NIR) device predicts cardiovascular (CVD), coronary heart disease (CHD), and ischemic stroke events in a prospective population-based survey. The study population consisted of 2,842 men and 3,196 women, who participated in the FINRISK'92 survey. Obesity was assessed with BMI, waist circumference, and waist-to-hip ratio (WHR) and body fat percentage measured with an NIR. Mean length of follow-up was 9 years and 3 months. In Cox proportional hazards regression analyses for men, BMI, waist circumference, and WHR as well as body fat percentage were predictors of a CVD event when adjusted for age and for major risk factors. Hazard ratio (HR) per 1 s.d. was 1.27 (95% confidence interval: 1.10-1.48) for body fat percentage, 1.30 (1.16-1.46) for BMI, and 1.31 (1.16-1.50) for waist circumference. Among women, the body fat lost its predictive power in a fully adjusted model. Body fat percentage, BMI, waist circumference, and WHR were predictors of a CHD event both among men and women, whereas body fat percentage did not predict ischemic stroke among either gender. We observed that body fat percentage measured by an NIR device was a significant predictor of CVD and CHD events among men and women, but in our population-based survey, it did not provide any additional predictive power over and above the simpler measures, such as BMI or WHR.
我们评估了通过便携式近红外相互作用（NIR）设备测量的体脂肪百分比如何预测心血管疾病（CVD）、冠心病（CHD）和缺血性卒中事件在一项前瞻性基于人群的调查中。研究人群包括 2842 名男性和 3196 名女性，他们参加了 FINRISK'92 调查。肥胖通过 BMI、腰围和腰臀比（WHR）以及 NIR 测量的体脂肪百分比来评估。平均随访时间为 9 年 3 个月。在男性的 Cox 比例风险回归分析中，BMI、腰围和 WHR 以及体脂肪百分比在调整年龄和主要危险因素后是 CVD 事件的预测因素。每增加 1 个标准差的危险比（HR）为 1.27（95%置信区间：1.10-1.48），体脂肪百分比为 1.30（1.16-1.46），BMI 为 1.31（1.16-1.50），腰围为 1.31（1.16-1.50）。在女性中，体脂肪在完全调整模型中失去了预测能力。体脂肪百分比、BMI、腰围和 WHR 是男性和女性 CHD 事件的预测因素，而体脂肪百分比在男性和女性中均不能预测缺血性卒中。我们观察到，NIR 设备测量的体脂肪百分比是男性和女性 CVD 和 CHD 事件的重要预测因素，但在我们的基于人群的调查中，它并没有提供比 BMI 或 WHR 等更简单的测量方法提供更多的预测能力。
