Kiroshka V V, Tishchenko Iu O
Fiziol Zh (1994). 2010;56(4):121-9.
The aim of investigation was a comparative analysis of morphofunctional characteristics of allografts of mature ovarian tissue and neonatal ovary depending on initial hormonal status of recipient animals. Rats' mature ovarian tissue and neonatal ovary were transplanted under renal capsule simultaneously with ovariectomy and 2 months later. Data analysis indicated that the development of ovarian tissue transplant was determined by its maturity and initial hormonal status of recipient. Mature ovarian tissue transplants preserve morphology and endocrine function to the 60th day after transplantation to the recipient animals with the initial hormonal status that corresponds to the norm. Neonatal ovary transplants are developed to the mature stage following transplantation to recipients with hormonal status that corresponded to the ovariectomized animals, that is, low concentration of sex hormones and an increased level of follicle-stimulating hormone.
本研究的目的是根据受体动物的初始激素状态，对成熟卵巢组织同种异体移植和新生卵巢的形态功能特征进行比较分析。在切除大鼠卵巢的同时，将大鼠成熟卵巢组织和新生卵巢移植到肾被膜下，2个月后进行观察。数据分析表明，卵巢组织移植的发育取决于其成熟度和受体的初始激素状态。将成熟卵巢组织移植到初始激素状态正常的受体动物后，其形态和内分泌功能可在移植后60天内得以保留。将新生卵巢移植到激素状态与去卵巢动物相似（即性激素浓度低、促卵泡激素水平升高）的受体后，可发育至成熟阶段。
