Krasnoperov V G, Shamotienko O G, Grishin E V
Bioorg Khim. 1990 Nov;16(11):1567-9.
A method of the isolation of a crustacea-specific neurotoxin from the venom of the Latrodectus mactans tredecimguttatus spider by means of ion exchange chromatography on Mono Q and Mono S columns and hydrophobic chromatography on Phenyl-Superose column has been developed. LD50 of the toxin has been elucidated.
已开发出一种通过在Mono Q和Mono S柱上进行离子交换色谱以及在苯基超琼脂糖柱上进行疏水色谱,从间斑寇蛛毒液中分离甲壳纲特异性神经毒素的方法。已阐明该毒素的半数致死剂量(LD50)。