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当前和未来的药代动力学和药代动力学-药效学建模和模拟方向:欧洲第 19 届年会的群体方法学研究组。

Current and future directions of pharmacokinetic and pharmacokinetic-pharmacodynamic modelling and simulation: population approach group in Europe 19th annual meeting.

机构信息

Institute of Pharmacy, Department of Clinical Pharmacy, Martin-Luther-Universitaet Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, 06120 Halle, Germany.

出版信息

Expert Opin Drug Metab Toxicol. 2010 Dec;6(12):1599-604. doi: 10.1517/17425255.2010.529899. Epub 2010 Oct 24.

DOI:10.1517/17425255.2010.529899
PMID:20969486
Abstract

The Population Approach Group in Europe meeting is the annual meeting of a group of scientists interested in quantitative pharmacology approaches. This meeting provides insights on new modelling approaches and applications thereof in different therapeutic areas and in different phases of drug development, in which modelling and simulation is set 'at work'. These meeting highlights mainly focus on the contributions pertinent to this journal, such as physiology-based pharmacokinetic modelling, modelling of pharmacokinetic-pharmacodynamic relationships (including binary/categorical end points) in non-clinical studies and also include presentations of junior scientists in the annual Lewis Sheiner Student Session.

摘要

欧洲人群方法学研究组会议是对定量药理学方法感兴趣的科学家的年度会议。本次会议提供了在不同治疗领域和药物研发不同阶段的新模型方法及其应用的深入见解,其中模型和模拟“发挥了作用”。这些会议重点主要集中在与本期刊相关的贡献,例如基于生理学的药代动力学模型、非临床研究中药代动力学-药效动力学关系(包括二项/分类终点)的模型,以及在年度刘易斯·谢纳学生会议上介绍初级科学家的研究。

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