Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Dermatol Surg. 2010 Nov;36 Suppl 3:1886-92. doi: 10.1111/j.1524-4725.2010.01778.x.
The new 20 mg/mL hyaluronic acid (HA) dermal filler is a smooth, highly cohesive, viscous formulation developed to restore volume in aesthetic facial rejuvenation. OBJECTIVE Evaluate clinical experience with 20 mg/mL HA dermal filler to date and comment on its current and potential uses within the facial rejuvenation treatment paradigm.
In this paper, the authors review the unique physical and chemical properties of 20 mg/mL HA dermal filler as well as clinical experience with the product to date.
Overall, the 20 mg/mL smooth, cohesive, viscous HA filler was especially effective in restoring volume in the malar region and chin. Volume loss resolved significantly in patients in clinical trials(1) and treatment effects were observed to be maintained from six to 18 months.(2) Physicians reported the agent was highly effective as well as easy to inject, sculpt and mold. The treatment was generally well tolerated and no instances of product migration from the injection site have been reported. Patient satisfaction was high, with the vast majority of trial participants acknowledging they would return for additional treatment and recommend the treatment to friends.(1,2)
Initial experience shows the 20 mg/mL smooth, cohesive, viscous HA filler to be a useful addition to the facial rejuvenation armamentarium when used both alone and in combination with BTX-A.
新型 20 毫克/毫升透明质酸(HA)真皮填充剂是一种质地光滑、高度凝聚、粘性的配方,旨在恢复美学面部年轻化中的体积。
评估迄今为止 20 毫克/毫升 HA 真皮填充剂的临床经验,并对其在面部年轻化治疗方案中的当前和潜在用途进行评论。
本文作者回顾了 20 毫克/毫升 HA 真皮填充剂的独特物理和化学特性以及迄今为止的临床经验。
总体而言,20 毫克/毫升光滑、凝聚、粘性的 HA 填充剂在恢复颊部和下巴的体积方面特别有效。临床试验中,患者的体积损失显著解决(1),治疗效果从六个月到十八个月观察到维持。(2)医生报告该制剂非常有效,易于注射、雕刻和塑造。治疗通常耐受性良好,没有报告产品从注射部位迁移的情况。患者满意度很高,绝大多数试验参与者承认他们将返回接受额外治疗,并向朋友推荐该治疗方法。(1,2)
初步经验表明,当单独使用和与 BTX-A 联合使用时,20 毫克/毫升光滑、凝聚、粘性的 HA 填充剂是面部年轻化武器库中的有用补充。