Groupe de recherche sur les maladies infectieuses du porc, Faculté de Médecine Vétérinaire, Université de Montréal, C.P. 5000, Saint-Hyacinthe, Québec J2S 7C6, Canada.
Anim Health Res Rev. 2010 Dec;11(2):97-121. doi: 10.1017/S1466252310000149. Epub 2010 Oct 25.
Bacterial biofilms are structured communities of bacterial cells enclosed in a self-produced polymer matrix that is attached to a surface. Biofilms protect and allow bacteria to survive and thrive in hostile environments. Bacteria within biofilms can withstand host immune responses, and are much less susceptible to antibiotics and disinfectants when compared with their planktonic counterparts. The ability to form biofilms is now considered a universal attribute of micro-organisms. Diseases associated with biofilms require novel methods for their prevention, diagnosis and treatment; this is largely due to the properties of biofilms. Surprisingly, biofilm formation by bacterial pathogens of veterinary importance has received relatively little attention. Here, we review the current knowledge of bacterial biofilms as well as studies performed on animal pathogens.
细菌生物膜是由细菌细胞组成的结构体，被自身产生的聚合物基质包裹，并附着在表面上。生物膜可以保护细菌，并使其在恶劣环境中生存和繁殖。生物膜内的细菌可以抵抗宿主的免疫反应，并且与浮游细菌相比，它们对抗生素和消毒剂的敏感性要低得多。形成生物膜的能力现在被认为是微生物的普遍特征。与生物膜相关的疾病需要新的方法来预防、诊断和治疗；这在很大程度上是由于生物膜的特性。令人惊讶的是，兽医重要病原体的细菌生物膜形成受到的关注相对较少。在这里，我们回顾了关于细菌生物膜的现有知识，以及在动物病原体上进行的研究。
