Department of Paediatrics, Hammersmith House, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.
Semin Fetal Neonatal Med. 2011 Feb;16(1):36-41. doi: 10.1016/j.siny.2010.10.002.
Circulatory failure plays a key role in the pathogenesis of mortality and key morbidity such as cerebral injury in the preterm infant. However awareness of the pathophysiology of circulatory failure itself is not well understood. Similarly there is significant uncertainty over optimal treatment approaches, particularly for inotropic therapies. Current uncertainties are perpetuated by difficulties with accurately assessing circulatory function. Cardiac magnetic resonance (CMR) imaging has produced significant advances in understanding of adult circulatory function, and acts as a powerful biomarker for interventional studies. Although routine circulatory assessment by CMR in the neonatal population is not currently a realistic goal, it could provide insights into pathophysiology; and act as an outcome measure in clinical trials in small numbers of infants in specialist centres. This review focuses on available CMR techniques, scope for use in the neonatal population, and our initial experience with the technique.
循环衰竭在早产儿的死亡率和主要发病率（如脑损伤）的发病机制中起着关键作用。然而，人们对循环衰竭本身的病理生理学的认识还不够清楚。同样，对于最佳治疗方法，特别是对于正性肌力治疗方法，也存在很大的不确定性。目前的不确定性是由于准确评估循环功能存在困难而造成的。心脏磁共振（CMR）成像在理解成人循环功能方面取得了重大进展，并且是介入研究的有力生物标志物。尽管目前对新生儿人群进行常规 CMR 循环评估还不切实际，但它可以深入了解病理生理学，并在专门中心的少数婴儿临床试验中作为一种结果衡量标准。这篇综述主要关注现有的 CMR 技术、在新生儿人群中的使用范围以及我们在该技术方面的初步经验。
