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No replication of genotype effect of 5-HTTLPR on cortisol response to social stress in larger adolescent sample.

作者信息

Bouma Esther, Riese Harriette, Nederhof Esther, Ormel Johan, Oldehinkel Albertine

出版信息

Biol Psychiatry. 2010 Dec 1;68(11):e33-4; author reply e35. doi: 10.1016/j.biopsych.2010.04.041.

DOI:10.1016/j.biopsych.2010.04.041
PMID:20970779
Abstract
摘要

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No replication of genotype effect of 5-HTTLPR on cortisol response to social stress in larger adolescent sample.在更大规模的青少年样本中,5-羟色胺转运体基因连锁多态性区域(5-HTTLPR)的基因型对皮质醇对社交压力反应的影响不存在复制效应。
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引用本文的文献

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BJPsych Open. 2018 Jun 22;4(4):180-185. doi: 10.1192/bjo.2018.23. eCollection 2018 Jul.
2
DNA methylation profiles within the serotonin transporter gene moderate the association of 5-HTTLPR and cortisol stress reactivity.血清素转运体基因内的DNA甲基化谱调节5-羟色胺转运体基因启动子多态性(5-HTTLPR)与皮质醇应激反应性之间的关联。
Transl Psychiatry. 2014 Sep 16;4(9):e443. doi: 10.1038/tp.2014.88.
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Increased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins.
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Cogn Emot. 2013;27(2):193-216. doi: 10.1080/02699931.2012.712950. Epub 2012 Aug 24.
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Am J Psychiatry. 2012 Apr;169(4):397-405. doi: 10.1176/appi.ajp.2011.10111699.