Pflug B, Köhler W, Carella A B, Schmidt K P, Demisch L
Zentrum der Psychiatrie, J.W. Goethe-Universität, Frankfurt/Main, F.R.G.
Chronobiol Int. 1990;7(5-6):463-5. doi: 10.3109/07420529009059157.
Rubidium (Rb+) has an antidepressive effect and shortens the circadian period in animals, whereas Li+, another alcalic metal, lengthens it. When we treated a depressive Li+ nonresponder with Rb+, we found an improvement of depression as well as a phase advance of the temperature rhythm in relation to the rest-activity rhythm.
铷(Rb+)具有抗抑郁作用,并能缩短动物的昼夜节律周期,而另一种碱金属锂(Li+)则会延长该周期。当我们用铷(Rb+)治疗对锂(Li+)无反应的抑郁症患者时,我们发现患者的抑郁症状有所改善,并且体温节律相对于休息-活动节律出现了相位提前。