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铷和锂治疗患者的神经纤维不应期

Nerve fibre refractory period in patients treated with rubidium and lithium.

作者信息

Betts R P, Paschalis C, Jarratt J A, Jenner F A

出版信息

J Neurol Neurosurg Psychiatry. 1978 Sep;41(9):791-3. doi: 10.1136/jnnp.41.9.791.

Abstract

Nerve fibre refractory period distributions have been measured on the median nerves of six manic-depressive patients controlled with lithium carbonate, three chronic patients (two manic-depressives and one catatonic schizophrenic) controlled with rubidium chloride, and eight normal volunteers. Rubidium prolonged the refractory periods of all nerve fibres while lithium increased only the longer refractory periods.

摘要

已对六名用碳酸锂控制病情的躁郁症患者、三名用氯化铷控制病情的慢性病患者(两名躁郁症患者和一名紧张型精神分裂症患者)以及八名正常志愿者的正中神经进行了神经纤维不应期分布的测量。铷延长了所有神经纤维的不应期,而锂仅增加了较长的不应期。

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引用本文的文献

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The permeability of frog muscle fibres to lithium ions.蛙肌纤维对锂离子的通透性。
J Physiol. 1959 Oct;147(3):626-38. doi: 10.1113/jphysiol.1959.sp006265.
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Rubidium and lithium: opposite effects on amine-mediated excitement.
Science. 1971 Jun 25;172(3990):1355-7. doi: 10.1126/science.172.3990.1355.
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Rubidium: a potential modifier of affect and behaviour.
Nature. 1969 Jul 19;223(5203):321-2. doi: 10.1038/223321a0.
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