Division of Endocrinology & Metabolism, Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, South Korea.
Diabetes Res Clin Pract. 2011 Jan;91(1):e8-e10. doi: 10.1016/j.diabres.2010.09.025.
We analyzed data of 35,624 non-diabetic Koreans using fasting plasma glucose (FPG) criteria and HbA1c criteria in screening for diabetes. Among the 1,491 subjects newly diagnosed with diabetes, 473 (31.6%) met the FPG criteria only (≥7.0mmol/l), 350 (23.5%) met HbA1c criteria only (≥6.5%), and 668 (44.9%) met both criteria. The DM-by-HbA1c group had significantly older age, higher proportion of women, and lower hemoglobin concentration. The DM-by-FPG group had higher systolic and diastolic blood pressure, fasting serum insulin, and HOMA-IR. Further studies are needed to determine which of these criteria is superior in predicting the risks of long-term vascular complications of diabetes.
我们使用空腹血糖(FPG)标准和 HbA1c 标准分析了 35624 名非糖尿病韩国人的数据,以筛查糖尿病。在新诊断出的 1491 名糖尿病患者中,有 473 名(31.6%)仅符合 FPG 标准(≥7.0mmol/l),350 名(23.5%)仅符合 HbA1c 标准(≥6.5%),668 名(44.9%)符合这两个标准。DM-by-HbA1c 组的年龄明显更大,女性比例更高,血红蛋白浓度更低。DM-by-FPG 组的收缩压和舒张压、空腹血清胰岛素和 HOMA-IR 更高。需要进一步的研究来确定这些标准中的哪一个在预测糖尿病长期血管并发症的风险方面更优越。