Copenhagen City Heart Study, Bispebjerg Hospital, Copenhagen, Denmark.
Int J Occup Med Environ Health. 2010;23(3):217-24. doi: 10.2478/v10001-010-0031-6.
To test the usefulness of the Demand-Control Model as predictor for ischemic heart disease (IHD).
One thousand one hundred forty six actively employed men and women from the general population of Copenhagen participated at baseline in 1993-1994. They filled in questionnaires on the Demand-Control Model, job title, work place, civil status, family income, leisure time activity, smoking, medication, social support, social relations, conflicts, job responsibility, satisfaction, and insecurity and went through a medical examination, including measurements of coronary risk factors. All deaths and hospital admissions due to IHD, including first myocardial infarction (MI) in the cohort were traced in the Danish registries of deaths and hospital admissions to June 2007.
104 cases of first time hospitalisation or death due to IHD including 49 cases of MI occurred during 14 years follow up. Odds ratio (OR) compared to the relaxed group was 1.1 (0.1-3.1) among women and 1.6 (0.4-4.9) among men after confounder adjustment. Neither demands nor control were significantly associated with IHD. Among men 50 years of age or more, the risk for IHD was, however, elevated in the job strain group and the active group (OR = 3.5 and 3.2 respectively). Job insecurity was, however, strongly associated with IHD in men (OR = 2.7 (1.1-5.6)) after all adjustments. The risk was increased for MI too (OR = 2.7 (1.2-6.1)). Among women, the only significant association with IHD was for job dissatisfaction (OR = 3.0 (1.2-7.6)).
In this population and in a period and society characterized by relative wealth and increasing employment rates, the Demand-control Model did not predict IHD. However, the feeling of job insecurity predicted both IHD and MI among men and job dissatisfaction predicted IHD among women.
检验需求-控制模型(Demand-Control Model)对缺血性心脏病(IHD)的预测作用。
1993-1994 年,来自哥本哈根普通人群的 1146 名在职男性和女性参与了研究。他们填写了关于需求-控制模型、职称、工作场所、婚姻状况、家庭收入、业余活动、吸烟、药物治疗、社会支持、社会关系、冲突、工作责任、满意度和不安全感的问卷,并接受了体检,包括冠状动脉风险因素的测量。在 2007 年 6 月之前,通过丹麦的死亡和住院登记处追踪了该队列中所有因 IHD 导致的死亡和住院情况,包括首次心肌梗死(MI)。
在 14 年的随访中,发生了 104 例首次因 IHD 住院或死亡的病例,其中包括 49 例 MI。调整混杂因素后,与放松组相比,女性的比值比(OR)为 1.1(0.1-3.1),男性为 1.6(0.4-4.9)。需求和控制均与 IHD 无显著相关性。然而,对于 50 岁及以上的男性,工作紧张组和活跃组的 IHD 风险增加(OR 分别为 3.5 和 3.2)。然而,在所有调整后,男性的工作不安全感与 IHD 强烈相关(OR=2.7(1.1-5.6))。MI 的风险也增加了(OR=2.7(1.2-6.1))。对于女性,与 IHD 唯一显著相关的是工作不满(OR=3.0(1.2-7.6))。
在这一人群中,在一个相对富裕和就业率不断提高的时期和社会中,需求-控制模型不能预测 IHD。然而,工作不安全感的感觉预测了男性的 IHD 和 MI,而工作不满预测了女性的 IHD。