工作时长与心血管疾病风险之间的剂量反应关系：收入动态面板研究的结果
Dose-Response Relation Between Work Hours and Cardiovascular Disease Risk: Findings From the Panel Study of Income Dynamics.
作者信息
Conway Sadie H, Pompeii Lisa A, Roberts Robert E, Follis Jack L, Gimeno David
机构信息
University of Texas Health Science Center, School of Public Health, Houston (Drs Conway, Pompeii); University of Texas Health Science Center, School of Public Health, San Antonio (Drs Roberts, Gimeno); and University of St. Thomas, Houston, Texas (Dr Follis).
出版信息
J Occup Environ Med. 2016 Mar;58(3):221-6. doi: 10.1097/JOM.0000000000000654.
Abstract
OBJECTIVES
The aim of this study was to examine the presence of a dose-response relationship between work hours and incident cardiovascular disease (CVD) in a representative sample of U.S. workers.
METHODS
A retrospective cohort study of 1926 individuals from the Panel Study of Income Dynamics (1986 to 2011) employed for at least 10 years. Restricted cubic spline regression was used to estimate the dose-response relationship of work hours with CVD.
RESULTS
A dose-response relationship was observed in which an average workweek of 46 hours or more for at least 10 years was associated with an increased risk of CVD. Compared with working 45 hours per week, working an additional 10 hours per week or more for at least 10 years increased CVD risk by at least 16%.
CONCLUSION
Working more than 45 work hours per week for at least 10 years may be an independent risk factor for CVD.
摘要
目的
本研究旨在在美国工人的代表性样本中检验工作时长与心血管疾病（CVD）发病之间是否存在剂量反应关系。
方法
对收入动态面板研究（1986年至2011年）中1926名就业至少10年的个体进行回顾性队列研究。采用受限立方样条回归估计工作时长与心血管疾病的剂量反应关系。
结果
观察到一种剂量反应关系，即至少10年平均每周工作46小时或更长时间与心血管疾病风险增加相关。与每周工作45小时相比，每周额外工作10小时或更多且至少持续10年，心血管疾病风险至少增加16%。
结论
每周工作超过45小时且至少持续10年可能是心血管疾病的一个独立危险因素。
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