Department of Chemistry and Center for Nanoscience, Ludwig-Maximilians-Universität München, Butenandtstr. 11, 81377 München, Germany.
Chem Soc Rev. 2010 Dec;39(12):4731-40. doi: 10.1039/c0cs00107d. Epub 2010 Oct 25.
Mesoporous materials have a high potential for a number of different applications in Materials Science such as in molecular sieving, as masks for the formation of nanometre-sized metallic wires, as novel drug-delivery systems or as advanced host systems for catalysis. For many of these applications a thorough understanding of the interaction of guest molecules within the host matrix is required. In this tutorial review, we cover recent single-molecule experiments that allow the investigation of host-guest dynamics with unprecedented detail. We will show how molecules diffusing in samples with (almost) perfect domain ordering still show a large heterogeneity in their mobility and interaction with the host. With the presented methodology it is now possible to dramatically improve our understanding of host-guest interactions and in return develop new nano-structured mesoporous materials with properties optimised for a certain application.
介孔材料在材料科学的许多不同应用中具有很高的潜力，例如在分子筛、纳米尺寸金属线形成的掩模、新型药物输送系统或作为先进的催化主系统。对于许多这些应用，需要深入了解客体分子在主体基质中的相互作用。在本教程综述中，我们介绍了最近的单分子实验，这些实验允许以前所未有的细节研究主体-客体动力学。我们将展示在（几乎）具有完美畴序的样品中扩散的分子如何仍然表现出其在流动性和与主体相互作用方面的很大异质性。通过所提出的方法，现在有可能极大地提高我们对主体-客体相互作用的理解，并反过来开发具有针对特定应用优化的性能的新型纳米结构化介孔材料。
